Everything You Need to Know About Low Dose Naltrexone

Low-dose Naltrexone (LDN) is safe, non-toxic, and inexpensive therapy being used to treat patients with chronic pain, autoimmune diseases, CNS diseases, and certain cancers. Before you speak with your physician, learn more about the benefits of low dose naltrexone and whether it could be a good option for you.

What is Low Dose Naltrexone?

Naltrexone was first prescribed by physicians to treat opioid addictions at the dose of 50mg to 100mg per day. Today, prescribers are using “low” or “ultra-low” doses of Naltrexone to treat chronic pain. These doses are between 1 to 5 mg–a tenth of the typical FDA-approved treatment dosage.

Benefits of Low Dose Naltrexone

Low-dose Naltrexone is able to treat and alleviate symptoms for a wide variety of medical conditions, including:

  • Autoimmune diseases

    • Multiple Sclerosis

    • Rheumatoid Arthritis

    • Crohn’s Disease

    • Ulcerative Colitis

    • Lupus.

  • CNS diseases

    • Fibromyalgia

    • Parkinson’s Disease

    • Alzheimer’s Disease

    • Chronic Fatigue Syndrome.


  • Depression

  • Certain Cancers

How Does Low-Dose Naltrexone Work?

Naltrexone works by temporarily binding and blocking opioid receptors on cells, which produce endorphins. Studies have shown that naltrexone has anti-inflammatory effects at lower doses and is easily tolerated. Considering the consequences of long-term opioid use for chronic pain, low-dose Naltrexone has emerged as an alternative for pain and fatigue management.

What Are the Side Effects?

One of the most exciting aspects of LDN is the low reported incidence of adverse side effects. Studies have shown no withdrawal symptoms when treatment is stopped due to its low dosage. In some cases, patients may report vivid dreams, n

We Compound Low-Dose Naltrexone

If a patient is a good candidate for low-dose Naltrexone, they can fill their prescription at our compounding pharmacy. Central Drugs is able to offer all dosage forms (capsules, oral suspension, topical cream) of LDN at a low cost for patients. If you have a question about low-dose Naltrexone, please give us a call at (877) 447-7077 or email us at clinicalrph@centraldrugsrx.com.